NATIVA

NATIVA

The non-invasive prenatal screening test capable of identifying the main chromosomal abnormalities present in the fetus and the sex of the unborn child

NATIVA is aimed at any woman during pregnancy who wants to detect aneuploidy of chromosomes 21, 18, 13 (Down syndrome, Edwards syndrome, Patau syndrome), aneuploidy of the sex chromosomes (Turner syndrome, Klinefelter syndrome, Trisomy X chromosome, Jacobs syndrome), rare chromosomal abnormalities (RAAs, RATs), partial deletions and duplications (CNVs) and microdeletions.

NATIVA is performed with a maternal blood sample, through which it is possible to analyze the fragments of the circulating fetal DNA.

NATIVA can be performed from the 10th to the 18th week of gestation and, unlike invasive diagnostic tests, it does not present any risks for the mother and the baby.

Thanks to the greater sensitivity and specificity compared to conventional screening tests, NATIVA decreases the use of invasive diagnostic tests, reducing the risk of abortion related to them.

For the reporting of the Test there are 5 to 7 working days from when the biological sample arrives at the laboratory.

To book NATIVA send an e-mail to customerservice@xbiogem.it

What does it analyze

  • - Trisomies 21, 18, 13;
  • - Aneuploidy of the sex chromosomes (XXX, XO, XXY, XYY);
  • - Fetal sex analysis;
  • - For single and twin pregnancies;
  • - CE / IVD certification;
  • Analyzed in the BioRep laboratories, in Italy

  • - Trisomies 21, 18, 13;
  • - Aneuploidy of the sex chromosomes (XXX, XO, XXY, XYY);
  • - Microdeletions (22q 11.2, 1p 36, 15q 11.2, 5p 15.3, 4p 16.3);
  • - Fetal sex analysis;
  • - Only for single pregnancies;
  • Analyzed in the laboratories of Illumina, California

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  • - Trisomies 21, 18, 13;
  • - Aneuploidy of the sex chromosomes (XXX, XO, XXY, XYY);
  • - Trisomies of all chromosomes 1-22 (RATs);
  • - Microdeletions (22q 11.2, 1p 36, 15q 11.2, 5p 15.3, 4p 16.3);
  • - Fetal sex analysis;
  • - Only for single pregnancies;
  • Analyzed in the laboratories of Illumina, California

  • - Aneuploidy 21, 18 and 13;
  • - Aneuploidy of the sex chromosomes (XXX, XO, XXY, XYY);
  • - Aneuploidy of all chromosomes 1-22 (RAAs);
  • - Deletions and partial duplications ≥ 7Mb on all chromosomes (CNVs);
  • - Fetal sex analysis;
  • - For single and twin pregnancies;
  • - CE / IVD certification;
  • Analyzed in the BioRep laboratories, in Italy

How does it work

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F.A.Q. - NATIVA

The test is indicated in case of:

  • - Pregnancy at risk in which invasive prenatal diagnosis is contraindicated;
  • - Pregnancy in which the combined test (levels of PAPP-A and hCG + nuchal translucency) provides a risk of chromosomal abnormality;
  • - Expectant mothers with previous abortions;
  • - Family history for chromosomal aneuploidies;

It can also be performed in the case of:

  • - Twin pregnancy;
  • - Assisted fertilization pregnancy (homologous or heterologous);
  • - Vanishing twin (vanishing twin syndrome);
  • - Twin pregnancies with more than two fetuses;
  • - Pregnant woman known to have cancer;
  • - Immunotherapy, radiotherapy or blood transfusion performed by the pregnant woman within the previous 3 months;
  • - Allogenic organ transplantation in the pregnant woman;
  • - Chromosomal mosaics present in the mother involving the chromosomes under investigation;

It is possible to request reimbursement in the form of indirect compensation, however it is advisable to first check with your health insurance the reimbursement of the service.

It is possible to contact XBIOGem at +39 06 3015 8224 from Monday to Thursday from 8:30 to 16:00 and on Friday from 8:30 to 14:00.