HPV Test

HPV Test

It is a simple, rapid and reliable test capable of diagnosing the presence of Human Papilloma Virus (HPV) in the uterine cervix.

Why is it useful to do HPV Test?

HPV testing is recommended:

  • For cervical cancer screening (from age 30)
  • For women with an altered Pap smear, for whom further diagnostic investigations are required (colposcopy, HPV Test)
  • In the follow-up of the treated patients (6/12 months after treatment for HPV-related lesions of the uterine cervix)
  • To book HPV Test send an email to customerservice@xbiogem.it

    What it analyses

    It is possible to choose between three different types of tests, which allow you to:

  • Detecting the presence of HPV and simultaneously identifying 14 high-risk genotypes (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68), including HPV16 and HPV18, which are known as major risk factors for cervical cancer.
  • Simultaneously detect and identify 28 HPV genotypes (including the 14 mentioned above), divided into 20 high-risk genotypes (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 69, 70, 73, 82) and 8 low-risk genotypes (6, 11, 40, 42, 43, 44, 54, 61).
  • Assess messenger RNA (mRNA) expression to identify (do not type) mRNA of 14 high-risk HPV genotypes with high sensitivity and specificity (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68).
  • How does it work


    F.A.Q. HPV Test

    The HPV test is a molecular technique that allows detecting the presence of the viral genome (DNA and/or mRNA), and therefore the presence of infection, sometimes before the cells of the cervix show abnormalities detectable by pap test or biopsy colposcopically guided.

    The test is performed on a cervico-vaginal cytological sample obtained with dry swab or thin-layer cytology performed by the gynecologist using the specially provided kit.

    The sample taken is analyzed by means of a test which is based on the amplification of HPV DNA and/or the detection of HPV mRNA by «Real-Time» PCR. The test is performed at the Microbiology Laboratory of the Fondazione Policlinico Universitario A. Gemelli IRCCS di Roma.

    The HPV Test report provides answers about the presence/absence of HPV Papilloma Virus. The test results must be interpreted by a medical specialist in light of the patient's clinical picture and other factors.

    The test provides three types of answers:

  • a positive response, which indicates the presence of HPV with reference to a specific HPV genotype among the 14 or 28 high and low risk analyzed.
  • a negative response, , indicating the absence of HPV among the 14 or 28 high-risk and low-risk genotypes analyzed.
  • The mRNA test if "positive" indicates that an HPV is integrated into the DNA of the cells of the uterine cervix.
  • The test cannot absolutely rule out an infection with genotypes that cannot be detected by the test.

    The price varies according to the type of test performed:

  • HPV 14 genes: €75
  • HPV 28 genes: €95
  • HPV Rna: 80€
  • For the execution of the test, 7 working days are foreseen from when the biological sample arrives at the laboratory.

    It is possible to request reimbursement in the form of indirect indemnity, however it is advisable to first check the reimbursement of the service with your health insurance company.

    You can contact XBIOGem on +39 06 3015 8224 from Monday to Thursday from 8.30 to 16:00 and on Friday from 8:30 to 14:00.

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