XForLife

XFor Life

XForLife offers non-invasive tests dedicated to prenatal and preconception screening and guarantee high quality standards at every stage of the production process and in data interpretation.

Why is it useful to do XForLife?

The XForLife tests offer specific screening both for the preconceptional and for the gestational phases and are able to detect, through a blood sample, potential inheritance of genetic diseases or fetal anomalies, in particular they allow to carry out the analysis for the Bi-test, preeclampsia and multiple abortion (HLA-G).

To book XForLife send an email to customerservice@xbiogem.it

What it analyses


BI-TEST OR COMBINED TEST

It is a type of test that determines the risk of having a fetus affected by Down Syndrome (trisomy 21), Edwards Syndrome (trisomy 18) and Patau Syndrome (trisomy 13) through a combined evaluation of various parameters: maternal age, ultrasound of nuchal translucency and dosing on maternal blood of two analytes: free-beta-hCG and PAPP-A.

The test is positive when it indicates a risk of trisomy equal to or greater than 1:250 (high risk). A negative test (risk < 1:1000, low risk) indicates a low risk of trisomies. One test could provide an intermediate risk (<1:250, >1:1000)

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PREECLAMPSIA

The test aims to perform the plasma dosage of PlGF and PAPP-A and is carried out between the 11th and 14th week of gestation. This dosage allows, in association with its clinical characteristics (BMI, age, ethnicity and smoking), with the plasma dosage of PAPP-A, size of the fetus (Crown Rump Length CRL) and with the data detected by the measurement of the mean arterial pressure (MAP) and mean uterine artery pulsatility index (UAPI), to identify early-onset cases.

The test results make it possible to personalize the preeclampsia risk of each pregnant woman in order to optimize clinical management; therefore they must be interpreted by a specialist physician in the context of the overall clinical picture of the pregnancy.

POLIABORTIVITY (HLA-G)

The execution of the genetic test is aimed at any individual who wants to determine the presence of the rs66554220 variant of the HLA-G gene, in order to be able to establish therapeutic regimens aimed at preventing or, in any case, making early abortion and frequent failure of Medically Assisted Procreation (MAP) techniques in cases where the genotype found is associated with altered levels of HLA-G.

The test can give a positive result if the presence of the rs66554220 polymorphism of the HLA-G gene is detected or a negative result if it is not detected. If the rs66554220 polymorphism is detected, the allelic status (homozygous or heterozygous) will be reported.

How does it work

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F.A.Q. XForLife

The execution of all three tests requires a simple blood sample, which will be analyzed at Policlinico Universitario Agostino Gemelli IRCCS.

For the Bi-Test and Preeclampsia it takes 5 working days, while for the HLA-G test (polyabortion) it takes 7 working days.

For a correct interpretation of the results, it is advisable to seek advice from a specialist doctor.

The sample, after carrying out the analysis and issuing the report, will be destroyed according to current legislation.

For the BI-TEST (Free-betaHCG + PAPP_A) the cost is 160 €, for Preeclampsia (PLGF+PAPP-A) the cost is 120 €, while for the complete test (plasma dosage of PAPP-A and free-betaHCG + PLGF) the cost is 190 €.

As for the multiple abortion test (HLA-G), the price of the Single Test is 160 €. The cost of the test for both partners is 290 €.

It is possible to request reimbursement in the form of indirect compensation , however it is advisable to check beforehand with your health insurance company the reimbursement of the service

You can contact XBIOGem on +39 06 3015 8224 Monday to Thursday from 8:30 to 16:00 and Friday from 8:30 to 14:00.

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